In a study in 9 healthy subjects pharmacokinetics of a 50-mgdose of fosfomycin were not significantly altered by two 400 mgdoses of cimetidine, given both night before and 30 minutesbefore fosfomycin.(See reference number 1)
1. Bergan T,Mastropaolo G, Di Mario F, Naccarato R. Pharmacokinetics of fosfomycin and influence of cimetidine and metoclopramide on the bioavailability of fosfomycin trometamol.New Trends in Urinary Tract Infections (eds Neu and Williams) Int Symp Rome 1987, pp 157–
66. Published in 1988.