The UK manufacturers of mifepristone say that efficacy ofcorticosteroids (included inhaled corticosteroids) is expected to bereduced in 3 to 4 days following use of mifepristone, because of antiglucocorticoid activity of mifepristone.(See reference number 1) Patients taking corticosteroids should be monitored during this time, andconsideration given to increasing corticosteroid dose. However, US manufacturers contraindicate use of mifepristonein those receiving long-term corticosteroid therapy.(See reference number 2)
Mifegyne (Mifepristone). Exelgyn Laboratories. UK Summary of product characteristics,February 2006.
Mifeprex (Mifepristone). Danco Laboratories,LLC. US Prescribing information, July 2005.