Clinical evidence,mechanism, importance and management
In 6 elderly patients acipimox 250mg three times daily for a week was found to have no significant effect on plasma digoxin levels,clinical con
dition,ECGs, plasma urea or electrolyte levels (See reference number 1). No special precautions during concurrent use would seem necessary.
1. Chijioke PC,Pearson RM, Benedetti S. Lack of acipimox-digoxin interaction in patient volunteers. Hum Exp Toxicol (1992) 11, 357–9.