The manufacturers of several of alpha blockers provide listsof drugs that are not expected to interact. These are shown in table 1 below,. In some cases these predictions are based on in vitro studies or from observation of clinical usage. Although thistype of data can provide a guide,remember that it gives only thebroadest indication of whether or not a drug interacts.
| Table 1 Drugs that are not expected to interact with alpha blockers as listed by the manufacturers | ||||
|---|---|---|---|---|
| Doxazosin1 | Prazosin2 | Tamsulosin3,4 | Terazosin5 | |
| Amitriptyline | No expected interaction (in vitro study) | |||
| Amoxicillin | No expected interaction | |||
| Antacids | No expected interaction | No expected interaction | ||
| Antidiabetic drugs | No expected interaction | No expected interaction with chlorpropamide, insulin, phenformin, tolazamide, or tolbutamide | No expected interaction with glibenclamide (in vitro study) | No expected interaction |
| Antigout drugs | No expected interaction with allopurinol, colchicine, or probenecid | No expected interaction with allopurinol | ||
| Anxiolytics and Hypnotics | No expected interaction with diazepam | No expected interaction with chlordiazepoxide or diazepam | No expected interaction with diazepam (in vitro study) | No expected interaction with diazepam |
| Chlorphenamine | No expected interaction | No expected interaction | ||
| Codeine | No expected interaction | No expected interaction | ||
| Cold and flu remedies | No expected interaction | No expected interaction with phenylephrine, phenylpropanolamine, or pseudoephedrine | ||
| Corticosteroids | No expected interaction | No expected interaction | ||
| Co-trimoxazole | No expected interaction | No expected interaction | ||
| Dextropropoxyphene (Propoxyphene) | No expected interaction | |||
| Erythromycin | No expected interaction | No expected interaction | ||
| Phenobarbital | No expected interaction | |||
| Paracetamol (Acetaminophen) | No expected interaction | No expected interaction | ||
| Procainamide | No expected interaction | |||
| Quinidine | No expected interaction | |||
| Salbutamol | No expected interaction (in vitro study) | |||
| Simvastatin | No expected interaction (in vitro study) | |||